Composite skin carotenoid concentration is related to macular pigment volume: The Pharmanex BioPhotonic Scanner

INTRODUCTION

  • Carotenoids are a group of phytonutrients that play an important role in human health via their antioxidant and anti-inflammatory properties.
  • Three carotenoids lutein (L), zeaxanthin (Z) and meso-zeaxanthin (MZ) are exclusively found in the central part of the macula where they are commonly referred to as macular pigment (MP) [1]. Recent studies have also shown that L and Z are also present in the brain [2].
  • Measurement of these carotenoids in humans is challenging, costly and time consuming.
  • Invasive measurements include:
    Obtaining biological samples (blood, skin biopsies) for High Performance Liquid Chromatography (HPLC) analysis.
  • Minimally invasive measurements include:
    MP measurements using dual-wavelength autofluorescence.
  • With improvements in technology there is now the potential to non-invasively measure carotenoid status in the skin. Devices such as the Nu Skin Pharmanex S3 scanner measure total carotenoid concentration using Raman Spectroscopy.
  • This work compares a non-invasive skin carotenoid score (SCS) to macular pigment volume (MPV) measurements.

LINK TO GRAPHIC ARTICLE: Composite skin carotenoid concentration is related to macular pigment volume: The Pharmanex BioPhotonic Scanner